Drug group Corticosteroid

Overdose danger rating Low

Dependence rating Low

Prescription needed Yes

Available as generic Yes


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Be sure to tell your doctor if:

▼      You have had a peptic ulcer.

▼      You have glaucoma.

▼      You have had tuberculosis. T You suffer from depression. T You have any infection.

▼      You have diabetes.

▼ You have osteoporosis. T You are taking other medications.

Avoid exposure to chickenpox or shingles if you are on systemic treatment.


▼       No evidence of risk with drops or joint injections. Given by tablets in low doses, harm to the fetus is unlikely. Discuss with your doctor.


▼       No evidence of risk with drops or injections. Taken by mouth, it passes into the breast milk, but at low doses adverse effects on the baby are unlikely. Discuss with your doctor.

Infants and children

▼       Only given when essential. Reduced dose may be necessary.

Over 60

▼     Increased likelihood of adverse effects. Reduced dose may therefore be necessary.

Driving and hazardous work

▼     No known problems.


▼ Alcohol may increase the risk of peptic ulcers with prednisolone taken by mouth or injection; keep consumption low. No problems with other forms.

Prednisolone  PROLONGED USE

Prolonged systemic use is recommended only wheh essential as it can lead to such adverse effects as diabetes, glaucoma, cataracts, and fragile bones, arid may retard growth in children. Dosages are usually tailored to minimize these effects.





Brand names Alvedon, Calpol, Disprol, Hedex, Panadol , Panaleve, and many others.

Used in the following combined preparations Anadin Extra, Migraleve, Panadeine, Paradote, Tylex, and others

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general information

Although paracetamol has been known since the early 1900s, it was not widely u=ed as an analgesic until the 1950s. One of a group of drugs known as the non-opioid analgesics, it is kept in the home to relieve occasional bouts of mild pain and to reduce fever. It is suitable for children as well as adults.

One of the primary advantages of paracetamol is that it does not cause stomach upset or bleeding problems. This makes it a particularly useful

alternative for people who suffer from peptic ulcers or those who cannot tolerate aspirin. The drug is also safe for occasional use by those who are being treated with anticoagulants.

Paracetamol is dangerous when it is taken in overdose, and it is capable of causing serious damage to the liver and kidneys. Large doses of paracetamol may also be toxic if you regularly drink even moderate amounts of alcohol.

information for users

Follow instructions on the label. Call your doctor if symptoms worsen.

How taken

Tablets, capsules, liquid, suppositories.

Frequency and timing of doses

Every 4-6 hours as necessary, but not more than 4 doses per 24 hours in children.

Dosage range

Adults 500mg-1g per dose up to 4g daily. Children 60-120mg per dose (3 months- 1 year); 120-250mg per dose (1-5 years); 250-500mg per dose (6-12 years).

Onset of effect

Within 15-60 minutes.

Duration of action

Up to 6 hours.

Diet advice



Keep in a closed container in a cool, dry place out of the reach of children.

Missed dose

Take as soon as you remember if required to relieve pain. Otherwise do not take the missed dose, and take a further dose only when you are in pain.

Stopping the drug

Can be safely stopped as soon as you no longer need it.

overdose action

Seek immediate medical advice in all cases. Take emergency action if nausea, vomiting, or stomach pain occur.

possible adverse effects

Paracetamol has rarely been found to produce The drug should be stopped and your doctor any side effects when taken as recommended.

Symptom/effect FrequencyCommon Rare Discus doctorOnly if severe s withIn all cases Stop taking drug now Calldoctornow


Anticoagulants such as warfarin may need dosage adjustment if paracetamol is taken regularly in high doses.

quick reference

Drug group Non-opioid analgesic.

Overdose danger rating High

Dependence rating Low

Prescription needed No

Available as generic Yes

special precautions

Be sure to consult your doctor or pharmacist before using this drug if:

▼ You have long-term liver or kidney


You are taking other medications.


▼ No evidence of risk with occasional use.


▼ No evidence of risk.

Infants and children

▼       Infants under 3 months on doctor’s advice only. Reduced dose necessary up to 12 years.

Over 60

▼       No special problems.

Driving and hazardous work

No special problems.


Prolonged heavy alcohol intake in combination with paracetamol may substantially increase the risk of injury to the liver.

Cholestyramine reduces the absorption of paracetamol and may reduce its effectiveness.

prolonged use

You should not normally take this drug for longer than 48 hours except on the advice of your doctor. However, there is no evidence of harm from long-term use.